NMRAL1 anticorps

N° du produit ABIN5704605

Détail du produit anti-NMRAL1 anticorps

Antigène: NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMRAL1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogène: NmrA-like family domain containing 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05769(NMRAL1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur NMRAL1

Antigène: NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))

Autre désignation: NMRAL1 (NMRAL1 Produits)

Synonymes: anticorps HSCARG, anticorps SDR48A1, anticorps 1110025F24Rik, anticorps AI256624, anticorps RGD1311451, anticorps NmrA like redox sensor 1, anticorps NmrA-like family domain containing 1, anticorps NMRAL1, anticorps Nmral1

Sujet: Synonyms:HSCARG Background:Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.

Poids moléculaire: 33 kDa

ID gène: 57407

UniProt: Q9HBL8