SRGAP2 anticorps
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- Antigène Voir toutes SRGAP2 Anticorps
- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SRGAP2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogène
- SLIT-ROBO Rho GTPase activating protein 2
- Isotype
- IgG
- Top Product
- Discover our top product SRGAP2 Anticorps primaire
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- Indications d'application
- WB : 1:500-1:5000 IP : 1:500-1:5000 IHC : 1:20-1:200
- Commentaires
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mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab08225(SRGAP2 antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
- Autre désignation
- SRGAP2 (SRGAP2 Produits)
- Synonymes
- anticorps ARHGAP34, anticorps FNBP2, anticorps SRGAP2A, anticorps SRGAP3, anticorps 9930124L22Rik, anticorps AI448945, anticorps FBP2, anticorps Fnbp2, anticorps srGAP3, anticorps AI452337, anticorps Arhgap14, anticorps D130026O08Rik, anticorps Gbi, anticorps MEGAP, anticorps WRP, anticorps mKIAA0411, anticorps RGD1566016, anticorps srGAP2, anticorps srgap2a, anticorps wu:fb47h12, anticorps zgc:136814, anticorps fnbp2, anticorps srgap2, anticorps SLIT-ROBO Rho GTPase activating protein 2, anticorps SLIT-ROBO Rho GTPase activating protein 3, anticorps SLIT-ROBO Rho GTPase activating protein 2 L homeolog, anticorps SRGAP2, anticorps Srgap2, anticorps Srgap3, anticorps srgap2, anticorps srgap2.L
- Sujet
- Synonyms:ARHGAP34, FNBP2, Formin binding protein 2, KIAA0456, SRGAP2, srGAP3 Background:RAC1 GTPase activating protein(GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
- Poids moléculaire
- 130 kDa
- ID gène
- 23380
- UniProt
- O75044
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