MIA3 anticorps

N° du produit ABIN5704883

Détail du produit anti-MIA3 anticorps

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Immunogène: melanoma inhibitory activity family, member 3

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MIA3

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Autre désignation: MIA3 (MIA3 Produits)

Synonymes: anticorps CG11098, anticorps Dmel\\CG11098, anticorps TANGO1, anticorps MIA3, anticorps 9130229H14Rik, anticorps A930039G15Rik, anticorps AU022327, anticorps B230399H06Rik, anticorps C80126, anticorps Gm1525, anticorps Tango, anticorps ARNT, anticorps D320, anticorps TANGO, anticorps UNQ6077, anticorps Transport and Golgi organization 1, anticorps MIA family member 3, ER export factor, anticorps melanoma inhibitory activity family, member 3, anticorps melanoma inhibitory activity protein 3, anticorps melanoma inhibitory activity family member 3, anticorps melanoma inhibitory activity 3, anticorps Tango1, anticorps MIA3, anticorps LOC100055507, anticorps mia3, anticorps Mia3

Sujet: Synonyms:KIAA0268, TANGO, TANGO1 Background:Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).

Poids moléculaire: 250 kDa

ID gène: 375056

UniProt: Q5JRA6