UNC13A/Munc13-1 anticorps

N° du produit ABIN5704978

Détail du produit anti-UNC13A/Munc13-1 anticorps

Antigène: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC13A/Munc13-1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: unc-13 homolog A (C. elegans)

Isotype: IgG

Information d'application

Indications d'application: WB : 1:500-1:5000,IP:1:200-1:2000

Commentaires:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab09255(UNC13A antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur UNC13A/Munc13-1

Antigène: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Autre désignation: UNC13A/Munc13-1 (UNC13A Produits)

Synonymes: anticorps Munc13-1, anticorps Unc13h1, anticorps 2410078G03Rik, anticorps unc-13 homolog A, anticorps unc-13 homolog A (C. elegans), anticorps Unc13a, anticorps UNC13A

Sujet: Synonyms:KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A Background:UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.

Poids moléculaire: 27kDa

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis