MSL1 anticorps

N° du produit ABIN5705283

Détail du produit anti-MSL1 anticorps

Antigène: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: male-specific lethal 1 homolog (Drosophila)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MSL1

Antigène: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Autre désignation: MSL1 (MSL1 Produits)

Synonymes: anticorps MSL-1, anticorps hMSL1, anticorps 2810017F12Rik, anticorps 4121402D02Rik, anticorps 4930463F05Rik, anticorps AA682082, anticorps Msl-1, anticorps male specific lethal 1 homolog, anticorps male-specific lethal 1 homolog (Drosophila), anticorps MSL1, anticorps Msl1

Sujet: Synonyms:MSL1L1 Background:Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.

Poids moléculaire: 67 kDa

ID gène: 339287

UniProt: Q68DK7