TTI1 anticorps

N° du produit ABIN5705553

Détail du produit anti-TTI1 anticorps

Antigène: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTI1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Immunogène: KIAA0406

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5000,IP:1:500-1:5000

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab09093( KIAA0406 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TTI1

Antigène: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Autre désignation: TTI1 (TTI1 Produits)

Synonymes: anticorps KIAA0406, anticorps smg-10, anticorps 2610036D13Rik, anticorps AI449463, anticorps RGD1562582, anticorps TELO2 interacting protein 1, anticorps TTI1, anticorps Tti1

Sujet: Synonyms:TELO2-interacting protein 1 homolog,KIAA0406, SMG10,TTI1 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Poids moléculaire: 130kDa

ID gène: 9675

UniProt: O43156