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RRP8 anticorps

RRP8 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5705951
  • Antigène Voir toutes RRP8 Anticorps
    RRP8 (Ribosomal RNA Processing 8 (RRP8))
    Reactivité
    • 23
    • 11
    • 10
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 21
    • 2
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RRP8 est non-conjugé
    Application
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Immunogène
    ribosomal RNA processing 8, methyltransferase, homolog (yeast)
    Isotype
    IgG
    Top Product
    Discover our top product RRP8 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    human brain tissue were subjected to SDS PAGE followed by western blot with FNab07501(RRP8 antibody) at dilution of 1:1500

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze / thaw cycles.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    RRP8 (Ribosomal RNA Processing 8 (RRP8))
    Autre désignation
    RRP8 (RRP8 Produits)
    Synonymes
    anticorps KIAA0409, anticorps 1500003O22Rik, anticorps 2900001K19Rik, anticorps AW538116, anticorps RGD1308302, anticorps ribosomal RNA processing 8, anticorps ribosomal RNA processing 8, methyltransferase, homolog (yeast), anticorps RRP8, anticorps Rrp8
    Sujet
    Synonyms:KIAA0409, NML Background:Essential component of the eNoSC(energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9'(H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
    ID gène
    23378
    UniProt
    O43159
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