Bestrophin 1 anticorps

N° du produit ABIN5708195

Détail du produit anti-Bestrophin 1 anticorps

Antigène: Bestrophin 1 (BEST1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: Amino acids RFIYRLALTEEQQLMFEKLTLYCD were used as the immunogen for the Bestrophin 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Bestrophin 1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Bestrophin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: Bestrophin 1 (BEST1 Produits)

Synonymes: anticorps CG6264, anticorps Dbest, anticorps Dmel\\CG6264, anticorps anon-WO0118547.380, anticorps best, anticorps dBest1, anticorps dbest1, anticorps dmBest1, anticorps BEST1, anticorps VMD2, anticorps best-1, anticorps ARB, anticorps BEST, anticorps BMD, anticorps RP50, anticorps TU15B, anticorps Bmd, anticorps Vmd2, anticorps mBest1, anticorps Bestrophin 1, anticorps bestrophin 1, anticorps Best1, anticorps BEST1, anticorps best1, anticorps Bm1_25500

Sujet: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

UniProt: O76090