RTEL1 anticorps

N° du produit ABIN5708351

Détail du produit anti-RTEL1 anticorps

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTEL1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Réactivité croisée (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids R651-M756 was used as the immunogen for the RTEL1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RTEL1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RTEL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RTEL1

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Autre désignation: RTEL1 (RTEL1 Produits)

Synonymes: anticorps F18B13.3, anticorps F18B13_3, anticorps C20orf41, anticorps DKCB5, anticorps NHL, anticorps RTEL, anticorps bK3184A7.3, anticorps AI451565, anticorps AW540478, anticorps Rtel, anticorps RGD1306721, anticorps zgc:113114, anticorps regulator of telomere elongation helicase 1, anticorps RAD3-like DNA-binding helicase protein, anticorps RTEL1, anticorps rtel1, anticorps AT1G79950, anticorps LOC100286037, anticorps Rtel1

Sujet: The RTEL1 gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9NZ71