ELAVL1 anticorps

N° du produit ABIN577055

Détail du produit anti-ELAVL1 anticorps

Antigène: ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELAVL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Specificité: Greater than 95%

Purification: Purified IgG

Pureté: > 98 %

Immunogène: Synthetic Peptide

Clone: 19F12

Isotype: IgG1

Information d'application

Indications d'application: Works on IHC at 1/2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml

Buffer: PBS /glycerol

Stock: -20 °C

Références pour anticorps anti-ELAVL1 (ABIN577055)

Ni, Zhou, Song, Chen, Wang, Du, Zhang: "ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection." dans: Communications biology, Vol. 4, Issue 1, pp. 251, (2021) (PubMed).

Li, Lu, Dai, Torregroza, Hla, Evans: "Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1." dans: Blood, Vol. 123, Issue 9, pp. 1384-92, (2014) (PubMed).

Chang, Lu, Li, Hsieh, Xiong, Ghosh, Evans, Elemento, Hla: "Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis." dans: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4908-21, (2013) (PubMed).

García-Domínguez, Morello, Cisneros, Kontoyiannis, Frade: "Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis." dans: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1227-39, (2011) (PubMed).

Détails sur ELAVL1

Antigène: ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))

Autre désignation: HuR (ELAVL1 Produits)

Synonymes: anticorps ELAV1, anticorps HUR, anticorps Hua, anticorps MelG, anticorps HuR, anticorps 2410055N02Rik, anticorps W91709, anticorps elra, anticorps fa25f08, anticorps fb59a02, anticorps fc60g02, anticorps hua, anticorps wu:fa25f08, anticorps wu:fb59a02, anticorps wu:fc60g02, anticorps zHuA, anticorps Elavl1, anticorps Xel-1, anticorps elav1, anticorps elrA, anticorps hur, anticorps melg, anticorps p36, anticorps ElrA, anticorps elavl1, anticorps elavl1-a, anticorps elavl1-b, anticorps ELAV like RNA binding protein 1, anticorps ELAV-like protein 1, anticorps ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R), anticorps ELAV like RNA binding protein 1a, anticorps ELAV like RNA binding protein 1 L homeolog, anticorps ELAV like RNA binding protein 1 S homeolog, anticorps ELAVL1, anticorps Elavl1, anticorps elav1, anticorps elavl1a, anticorps elavl1.L, anticorps elavl1.S

Sujet: HuR (also called Elavl-1 or HuA) is a protein that binds to specific AU-rich elements in a mRNA and thereby upregulates its expression. The protein contains three RRM type RNA binding domains. The first and second RNA binding domains interact with the AU-rich element. HuR is a member of a family of proteins called the elav-like proteins. The other members, HuD, HuC, and HEL-N1 are predominantly expressed in neurons. Monoclonal 19F12 was designed by CLONEGENE and was generated against a unique HuR peptide and does not react with HuD, HuC, or Hel-N1.

Pathways: AMPK Signaling