MID1 anticorps

N° du produit ABIN5958299

Détail du produit anti-MID1 anticorps

Antigène: MID1 (Midline 1 (MID1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MID1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: BBBG 1,BBBG1,E3 ubiquitin-protein ligase Midline-1,Finger on X and Y mouse homolog of,FXY,GBBB 1,GBBB1,MID 1,Mid1,Midin,Midline 1 (Opitz/BBB syndrome),Midline 1,Midline 1 ring finger,Midline 1 RING finger protein,Midline-1,Midline1,OGS 1,OGS1,OS,OSX,Putative transcription factor XPRF,RING finger protein 59,RING finger protein Midline-1,RNF 59,RNF59,TRI18,TRI18,TRIM 18,TRIM18,Tripartite motif containing protein 18,Tripartite motif protein TRIM18,Tripartite motif-containing protein 18,XPRF,zinc finger on X and Y,mouse,homolog of,Zinc finger X and Y,ZNFXY

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the N-terminal region of human Midline-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MID1

Antigène: MID1 (Midline 1 (MID1))

Autre désignation: Midline-1 (MID1 Produits)

Synonymes: anticorps BBBG1, anticorps FXY, anticorps GBBB1, anticorps MIDIN, anticorps OGS1, anticorps OS, anticorps OSX, anticorps RNF59, anticorps TRIM18, anticorps XPRF, anticorps ZNFXY, anticorps 61B3-R, anticorps DXHXS1141, anticorps Fxy, anticorps Trim18, anticorps Midline1, anticorps bbbg1, anticorps fxy, anticorps gbbb1, anticorps midin, anticorps ogs1, anticorps osx, anticorps rnf59, anticorps trim18, anticorps xprf, anticorps znfxy, anticorps midline 1, anticorps midline 1 L homeolog, anticorps MID1, anticorps Mid1, anticorps mid1, anticorps mid1.L

Sujet: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

Poids moléculaire: 75kDa

ID gène: 4281

UniProt: O15344