SNX13 anticorps

N° du produit ABIN5964913

Détail du produit anti-SNX13 anticorps

Antigène: SNX13 (Sorting Nexin 13 (SNX13))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX13 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SNX13 (NP_055947.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SNX13

Antigène: SNX13 (Sorting Nexin 13 (SNX13))

Autre désignation: SNX13 (SNX13 Produits)

Synonymes: anticorps MGC142644, anticorps DKFZp469H181, anticorps Rgs-px1, anticorps mKIAA0713, anticorps RGS-PX1, anticorps sorting nexin 13, anticorps SNX13, anticorps Snx13

Sujet: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Poids moléculaire:

Observed_MW: 112kDa

Calculated_MW: 110kDa/112kDa

ID gène: 23161

UniProt: Q9Y5W8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling