SPAG6 anticorps (AA 180-290)

N° du produit ABIN6133998

Détail du produit anti-SPAG6 anticorps

Antigène: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Épitope: AA 180-290

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG6 est non-conjugé

Application: Western Blotting (WB)

Séquence: EIALKRIAAS ALSDIAKHSP ELAQTVVDAG AVAHLAQMIL NPDAKLKHQI LSALSQVSKH SVDLAEMVVE AEIFPVVLTC LKDKDEYVKK NASTLIREIA KHTPELSQLV V

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human SPAG6 (NP_758442.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SPAG6

Antigène: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Autre désignation: SPAG6 (SPAG6 Produits)

Synonymes: anticorps Repro-SA-1, anticorps pf16, anticorps PF16, anticorps RGD1310892, anticorps zgc:91805, anticorps SPAG6, anticorps repro-sa-1, anticorps DKFZp459D035, anticorps sperm associated antigen 6, anticorps sperm associated antigen 6-like, anticorps sperm associated antigen 6 L homeolog, anticorps SPAG6, anticorps Spag6l, anticorps Spag6, anticorps spag6, anticorps spag6.L

Sujet: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.,SPAG6,CT141,Repro-SA-1,pf16,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Stem Cells,Germline Stem Cells,SPAG6

Poids moléculaire: 30 kDa/49 kDa/52 kDa/55 kDa/63 kDa

ID gène: 9576

UniProt: O75602