MAPK14 anticorps (pThr180, pTyr182)

N° du produit ABIN6136138

Détail du produit anti-MAPK14 anticorps

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Épitope: pThr180, pTyr182

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK14 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MTGYV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Immunogène: A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK (NP_620581.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-MAPK14 (ABIN6136138)

Yuan, Zhu, Hong, Sun, Fang, Wu, Li: "The role of cPLA2 in Methylglyoxal-induced cell apoptosis of HUVECs." dans: Toxicology and applied pharmacology, Vol. 323, pp. 44-52, (2017) (PubMed).

Détails sur MAPK14

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Autre désignation: MAPK14 (MAPK14 Produits)

Synonymes: anticorps CSBP, anticorps CSBP1, anticorps CSBP2, anticorps CSPB1, anticorps EXIP, anticorps Mxi2, anticorps PRKM14, anticorps PRKM15, anticorps RK, anticorps SAPK2A, anticorps p38, anticorps p38ALPHA, anticorps CRK1, anticorps Csbp1, anticorps Csbp2, anticorps Exip, anticorps Hog, anticorps Prkm14, anticorps Prkm15, anticorps Sapk2A, anticorps p38Hog, anticorps p38alpha, anticorps p38b, anticorps zp38b, anticorps MAPK14, anticorps 186F5S, anticorps BG:DS00797.3, anticorps CG7393, anticorps D-p38, anticorps D-p38 MAPK, anticorps D-p38b, anticorps Dm p38b, anticorps Dmel\\CG7393, anticorps Dmp38b, anticorps Dp38, anticorps Dp38b, anticorps ESTS:186F5S, anticorps Mpk34C, anticorps anon-sts23, anticorps dp38b, anticorps p38 MAPK, anticorps p38 beta, anticorps p38B, anticorps p38Kb, anticorps p38beta, anticorps Crk1, anticorps p38-alpha, anticorps p38MAPK, anticorps p38a, anticorps csbp, anticorps mapk14a, anticorps mxi2, anticorps sapk2, anticorps sapk2a, anticorps AP22.98, anticorps AP22_98, anticorps ATMPK14, anticorps mitogen-activated protein kinase 14, anticorps SAPK2a, anticorps MAP kinase 14A, anticorps MAP kinase p38a, anticorps MAPK 14A, anticorps fk28c03, anticorps hm:zeh1243, anticorps wu:fk28c03, anticorps zp38a, anticorps P38C-CRK, anticorps mitogen-activated protein kinase 14, anticorps mitogen activated protein kinase 14, anticorps mitogen-activated protein kinase 14b, anticorps p38b MAP kinase, anticorps mitogen-activated protein kinase 14 S homeolog, anticorps mitogen-activated protein kinase 14a, anticorps CRK proto-oncogene, adaptor protein, anticorps MAPK14, anticorps Mapk14, anticorps mapk14b, anticorps p38b, anticorps mapk14.S, anticorps MPK14, anticorps mapk14a, anticorps CRK

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,MAPK14,CSBP,CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA,p38 MAPK,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,Protein phosphorylation,MAPK14

Poids moléculaire: 29 kDa/34 kDa/35 kDa/41 kDa

ID gène: 5600, 6300, 5603

UniProt: Q15759, P53778, O15264, Q16539

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins