PHAP1 anticorps (AA 1-170)

N° du produit ABIN6136909

Détail du produit anti-PHAP1 anticorps

Antigène: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Épitope: AA 1-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PHAP1

Antigène: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Autre désignation: ANP32A (ANP32A Produits)

Synonymes: anticorps C15orf1, anticorps HPPCn, anticorps I1PP2A, anticorps LANP, anticorps MAPM, anticorps PHAP1, anticorps PHAPI, anticorps PP32, anticorps Anp32, anticorps W91701, anticorps pp32, anticorps Anp32a, anticorps CG5784, anticorps CT18148, anticorps CT42180, anticorps Dmel\\CG5784, anticorps anon-EST:fe3A2, anticorps wu:fj36e08, anticorps zgc:55516, anticorps ANP32D, anticorps acidic nuclear phosphoprotein 32 family member A, anticorps acidic (leucine-rich) nuclear phosphoprotein 32 family, member A, anticorps CG5784 gene product from transcript CG5784-RB, anticorps acidic nuclear phosphoprotein 32 family member A L homeolog, anticorps ANP32A, anticorps Anp32a, anticorps Mapmodulin, anticorps anp32a, anticorps anp32a.L

Sujet: Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription. Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation. In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases complex. Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein and EP300/CREBBP-associated factor by histone masking. Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition. Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R. Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.,ANP32A,C15orf1,HPPCn,I1PP2A,LANP,MAPM,PHAP1,PHAPI,PP32,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,ANP32A

Poids moléculaire: 28 kDa

ID gène: 8125

UniProt: P39687