CD13 anticorps (AA 668-967)

N° du produit ABIN6136911

Détail du produit anti-CD13 anticorps

Antigène: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Épitope: AA 668-967

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: LASAHKVPVT LALNNTLFLI EERQYMPWEA ALSSLSYFKL MFDRSEVYGP MKNYLKKQVT PLFIHFRNNT NNWREIPENL MDQYSEVNAI STACSNGVPE CEEMVSGLFK QWMENPNNNP IHPNLRSTVY CNAIAQGGEE EWDFAWEQFR NATLVNEADK LRAALACSKE LWILNRYLSY TLNPDLIRKQ DATSTIISIT NNVIGQGLVW DFVQSNWKKL FNDYGGGSFS FSNLIQAVTR RFSTEYELQQ LEQFKKDNEE TGFGSGTRAL EQALEKTKAN IKWVKENKEV VLQWFTENSK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 668-967 of human CD13/CD13/ANPEP (NP_001141.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-CD13 (ABIN6136911)

Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." dans: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

Zhu, Liu, Wang, Luo, Shi, Wang, Peng, Chen, Fang, Xiao: "Contribution of porcine aminopeptidase N to porcine deltacoronavirus infection." dans: Emerging microbes & infections, Vol. 7, Issue 1, pp. 65, (2018) (PubMed).

Li, Chen, Ye, Guo, Muhanmmad Memon, Wu, He: "Comparative Proteome Analysis of Porcine Jejunum Tissues in Response to a Virulent Strain of Porcine Epidemic Diarrhea Virus and Its Attenuated Strain." dans: Viruses, Vol. 8, Issue 12, (2017) (PubMed).

Détails sur CD13

Antigène: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Autre désignation: ANPEP (ANPEP Produits)

Synonymes: anticorps APN, anticorps CD13, anticorps GP150, anticorps LAP1, anticorps P150, anticorps PEPN, anticorps A2AP, anticorps AAP, anticorps ALPHA-2-PI, anticorps API, anticorps PLI, anticorps AAT1, anticorps ALT1, anticorps GPT1, anticorps Gpt1, anticorps Apn, anticorps pepN, anticorps SC8E4A.13, anticorps 1300007J06Rik, anticorps 2310022B03Rik, anticorps ALT, anticorps Gpt-1, anticorps AP-M, anticorps AP-N, anticorps Cd13, anticorps Apm, anticorps KZP, anticorps Lap1, anticorps rAPN, anticorps APDE, anticorps p150, anticorps anpep, anticorps fb64c05, anticorps wu:fb64c05, anticorps zgc:136771, anticorps alanyl aminopeptidase, membrane, anticorps serpin family F member 2, anticorps glutamic--pyruvic transaminase, anticorps aminopeptidase N, anticorps aminopeptidase, anticorps aminopeptidase n, anticorps glutamic pyruvic transaminase, soluble, anticorps alanyl (membrane) aminopeptidase, anticorps membrane alanyl aminopeptidase, anticorps alanyl (membrane) aminopeptidase b, anticorps alanyl aminopeptidase, membrane L homeolog, anticorps ANPEP, anticorps SERPINF2, anticorps GPT, anticorps Gpt, anticorps Apn2, anticorps Apn1, anticorps SCO2643, anticorps pepN, anticorps Shewana3_0897, anticorps Alvin_1024, anticorps Ndas_3413, anticorps Saut_1544, anticorps Fbal_1877, anticorps ML5_3424, anticorps Despr_1988, anticorps Mesop_5365, anticorps Anpep, anticorps LOC101744250, anticorps anpepb, anticorps anpep.L

Sujet: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.,ANPEP,APN,CD13,GP150,LAP1,P150,PEPN,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,ANPEP

Poids moléculaire: 109 kDa

ID gène: 290

UniProt: P15144

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones