Aspartate beta Hydroxylase anticorps (AA 111-270)

N° du produit ABIN6137213

Détail du produit anti-Aspartate beta Hydroxylase anticorps

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Épitope: AA 111-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aspartate beta Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ERSTSEPAVP PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHETEHSYH VEETVSQDCN QDMEEMMSEQ ENPDSSEPVV EDERLHHDTD DVTYQVYEEQ AVYEPLENEG IEITEVTAPP EDNPVEDSQV IVEEVSIFPV EEQQEVPPDT

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 111-270 of human ASPH (NP_001158227.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Aspartate beta Hydroxylase

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Autre désignation: ASPH (ASPH Produits)

Synonymes: anticorps AAH, anticorps BAH, anticorps CASQ2BP1, anticorps HAAH, anticorps JCTN, anticorps junctin, anticorps 2310005F16Rik, anticorps 3110001L23Rik, anticorps AI848629, anticorps AW261690, anticorps AW561901, anticorps C79816, anticorps cI-37, anticorps aah, anticorps bah, anticorps jctn, anticorps MGC107896, anticorps cb971, anticorps fb69e10, anticorps fc06d04, anticorps fc95a08, anticorps wu:fb69e10, anticorps wu:fc06d04, anticorps wu:fc95a08, anticorps aspartate beta-hydroxylase, anticorps aspartate-beta-hydroxylase, anticorps aspartate beta-hydroxylase L homeolog, anticorps ASPH, anticorps Asph, anticorps asph, anticorps asph.L

Sujet: This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.,ASPH,AAH,BAH,CASQ2BP1,FDLAB,HAAH,JCTN,junctin,Signal Transduction,Neuroscience,Calcium Signaling,ASPH

Poids moléculaire: 21-34 kDa/83-85 kDa

ID gène: 444

UniProt: Q12797

Pathways: Positive Regulation of Endopeptidase Activity