AUH anticorps (AA 68-339)

N° du produit ABIN6137369

Détail du produit anti-AUH anticorps

Antigène: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Épitope: AA 68-339

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AUH est non-conjugé

Application: Western Blotting (WB)

Séquence: SSEMKTEDEL RVRHLEEENR GIVVLGINRA YGKNSLSKNL IKMLSKAVDA LKSDKKVRTI IIRSEVPGIF CAGADLKERA KMSSSEVGPF VSKIRAVIND IANLPVPTIA AIDGLALGGG LELALACDIR VAASSAKMGL VETKLAIIPG GGGTQRLPRA IGMSLAKELI FSARVLDGKE AKAVGLISHV LEQNQEGDAA YRKALDLARE FLPQGPVAMR VAKLAINQGM EVDLVTGLAI EEACYAQTIP TKDRLEGLLA FKEKRPPRYK GE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 68-339 of human AUH (NP_001689.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur AUH

Antigène: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Autre désignation: AUH (AUH Produits)

Synonymes: anticorps C77140, anticorps W91705, anticorps wu:fb81b10, anticorps zgc:101057, anticorps AU RNA binding methylglutaconyl-CoA hydratase, anticorps AU RNA binding protein/enoyl-coenzyme A hydratase, anticorps AU RNA binding protein/enoyl-CoA hydratase, anticorps AU RNA binding protein/enoyl-CoA hydratase S homeolog, anticorps AUH, anticorps Auh, anticorps auh, anticorps auh.S

Sujet: This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants.,AUH,AUH

Poids moléculaire: 32 kDa/35 kDa

ID gène: 549

UniProt: Q13825