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AXIN2 anticorps (AA 650-750)

AXIN2 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6137382
  • Antigène Voir toutes AXIN2 Anticorps
    AXIN2 (Axin 2 (AXIN2))
    Épitope
    • 15
    • 14
    • 11
    • 11
    • 11
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 650-750
    Reactivité
    • 78
    • 60
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 91
    • 2
    Lapin
    Clonalité
    • 80
    • 13
    Polyclonal
    Conjugué
    • 27
    • 9
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AXIN2 est non-conjugé
    Application
    • 70
    • 44
    • 30
    • 14
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    RSSPGERASR HHLWGGNSGH PRTTPRAHLF TQDPAMPPLT PPNTLAQLEE ACRRLAEVSK PPKQRCCVAS QQRDRNHSAT VQTGATPFSN PSLAPEDHKE P
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 650-750 of human AXIN2 (NP_004646.3).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." dans: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

  • Antigène
    AXIN2 (Axin 2 (AXIN2))
    Autre désignation
    AXIN2 (AXIN2 Produits)
    Synonymes
    anticorps AXIL, anticorps ODCRCS, anticorps axil, anticorps wu:fb37c08, anticorps zgc:111942, anticorps axin-2, anticorps xarp, anticorps MGC81576, anticorps arp-A, anticorps axin2, anticorps Axi1, anticorps Axil, anticorps Conductin, anticorps axin 2, anticorps axin 2 (conductin, axil), anticorps axin 2 (conductin, axil) S homeolog, anticorps AXIN2, anticorps axin2, anticorps axin2.S, anticorps Axin2
    Sujet
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.,AXIN2,AXIL,ODCRCS,axin-2,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell differentiation,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,AXIN2
    Poids moléculaire
    93 kDa
    ID gène
    8313
    UniProt
    Q9Y2T1
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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