CA8 anticorps (AA 1-290)

N° du produit ABIN6137796

Détail du produit anti-CA8 anticorps

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Épitope: AA 1-290

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CA8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MADLSFIEDT VAFPEKEEDE EEEEEGVEWG YEEGVEWGLV FPDANGEYQS PINLNSREAR YDPSLLDVRL SPNYVVCRDC EVTNDGHTIQ VILKSKSVLS GGPLPQGHEF ELYEVRFHWG RENQRGSEHT VNFKAFPMEL HLIHWNSTLF GSIDEAVGKP HGIAIIALFV QIGKEHVGLK AVTEILQDIQ YKGKSKTIPC FNPNTLLPDP LLRDYWVYEG SLTIPPCSEG VTWILFRYPL TISQLQIEEF RRLRTHVKGA ELVEGCDGIL GDNFRPTQPL SDRVIRAAFQ

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CA8 (NP_004047.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CA8

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Autre désignation: CA8 (CA8 Produits)

Synonymes: anticorps AW546993, anticorps Ca8, anticorps Cals, anticorps Cals1, anticorps Carp, anticorps wdl, anticorps zgc:110118, anticorps CA-VIII, anticorps CALS, anticorps CAMRQ3, anticorps CARP, anticorps carbonic anhydrase 8, anticorps carbonic anhydrase VIII, anticorps CAH8, anticorps Car8, anticorps ca8, anticorps CA8

Sujet: The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants.,CA8,CA-RP,CA-VIII,CALS,CAMRQ3,CARP,Cancer,Tumor biomarkers,CA8

Poids moléculaire: 32 kDa

ID gène: 767

UniProt: P35219