CDKN2B anticorps (AA 1-138)

N° du produit ABIN6138346

Détail du produit anti-CDKN2B anticorps

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Épitope: AA 1-138

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2B est non-conjugé

Application: Western Blotting (WB)

Séquence: MREENKGMPS GGGSDEGLAS AAARGLVEKV RQLLEAGADP NGVNRFGRRA IQVMMMGSAR VAELLLLHGA EPNCADPATL TRPVHDAARE GFLDTLVVLH RAGARLDVRD AWGRLPVDLA EERGHRDVAG YLRTATGD

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human CDKN2B (NP_004927.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CDKN2B

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Autre désignation: CDKN2B (CDKN2B Produits)

Synonymes: anticorps p14-INK4b, anticorps cdk4l, anticorps ink4b, anticorps mts2, anticorps p15, anticorps p15ink4b, anticorps tp15, anticorps CDK4I, anticorps INK4B, anticorps MTS2, anticorps P15, anticorps TP15, anticorps p15INK4b, anticorps AV083695, anticorps INK4b, anticorps p15(INK4b), anticorps CDKN2A, anticorps cyclin dependent kinase inhibitor 2B, anticorps Cyclin-dependent kinase 4 inhibitor B, anticorps cyclin-dependent kinase inhibitor 2B, anticorps cyclin-dependent kinase inhibitor 2B L homeolog, anticorps cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4), anticorps CDKN2B, anticorps cdn2b, anticorps cdkn2b, anticorps cdkn2b.L, anticorps Cdkn2b

Sujet: This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.,CDKN2B,CDK4I,INK4B,MTS2,P15,TP15,p15INK4b,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Stem Cells,CDKN2B

Poids moléculaire: 8 kDa/14 kDa

ID gène: 1030

UniProt: P42772

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases