COL1A2 anticorps (AA 500-600)

N° du produit ABIN6138839

Détail du produit anti-COL1A2 anticorps

Antigène: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Épitope: AA 500-600

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL1A2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: PTGDPGKNGD KGHAGLAGAR GAPGPDGNNG AQGPPGPQGV QGGKGEQGPP GPPGFQGLPG PSGPAGEVGK PGERGLHGEF GLPGPAGPRG ERGPPGESGA A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Collagen I/COL1A2 (NP_000080.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:25 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-COL1A2 (ABIN6138839)

Jiang, He, Zhu, Liang, Wang, Lu, Ren, Yi, Xiao, Wang: "Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model." dans: Experimental cell research, Vol. 369, Issue 2, pp. 325-334, (2018) (PubMed).

Yu, Zheng, Yang, Fei, Wang, Hou, Sun, Shen: "N-AC-l-Leu-PEI-mediated miR-34a delivery improves osteogenic differentiation under orthodontic force." dans: Oncotarget, Vol. 8, Issue 66, pp. 110460-110473, (2017) (PubMed).

Li, Wan, Zhang, Li, Han: "Quantitative proteomic analysis and comparison of two bone marrow stromal cell lines using the SILAC method." dans: Experimental hematology, Vol. 44, Issue 11, pp. 1059-1071, (2017) (PubMed).

Détails sur COL1A2

Antigène: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Autre désignation: COL1A2 (COL1A2 Produits)

Synonymes: anticorps AA960264, anticorps AI325291, anticorps Col1a-2, anticorps Cola-2, anticorps Cola2, anticorps oim, anticorps OI4, anticorps Gas-6, anticorps alpha2(I), anticorps hm:zehn2357, anticorps wu:fa98d05, anticorps wu:fa99g10, anticorps wu:fb04c08, anticorps wu:fb11d06, anticorps zehn2357, anticorps coagulation factor II, thrombin, anticorps collagen, type I, alpha 2, anticorps collagen type I alpha 2 chain, anticorps collagen type I alpha 2 L homeolog, anticorps growth arrest specific 6, anticorps F2, anticorps Col1a2, anticorps col1a2.L, anticorps COL1A2, anticorps Gas6, anticorps col1a2

Sujet: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.,COL1A2,OI4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Growth factor,Stem Cells,Mesenchymal Stem Cells,COL1A2

Poids moléculaire: 129 kDa

ID gène: 1278

UniProt: P08123