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DFFA anticorps (AA 1-331)

DFFA Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6139548
  • Antigène Voir toutes DFFA Anticorps
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    Épitope
    • 15
    • 14
    • 8
    • 8
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-331
    Reactivité
    • 73
    • 33
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 75
    • 9
    • 1
    Lapin
    Clonalité
    • 77
    • 8
    Polyclonal
    Conjugué
    • 61
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DFFA est non-conjugé
    Application
    • 82
    • 30
    • 14
    • 14
    • 13
    • 13
    • 12
    • 10
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MEVTGDAGVP ESGEIRTLKP CLLRRNYSRE QHGVAASCLE DLRSKACDIL AIDKSLTPVT LVLAEDGTIV DDDDYFLCLP SNTKFVALAS NEKWAYNNSD GGTAWISQES FDVDETDSGA GLKWKNVARQ LKEDLSSIIL LSEEDLQMLV DAPCSDLAQE LRQSCATVQR LQHTLQQVLD QREEVRQSKQ LLQLYLQALE KEGSLLSKQE ESKAAFGEEV DAVDTGISRE TSSDVALASH ILTALREKQA PELSLSSQDL ELVTKEDPKA LAVALNWDIK KTETVQEACE RELALRLQQT QSLHSLRSIS ASKASPPGDL QNPKRARQDP T
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human DFFA (NP_004392.1).
    Isotype
    IgG
    Top Product
    Discover our top product DFFA Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    Autre désignation
    DFFA (DFFA Produits)
    Synonymes
    anticorps DFF-45, anticorps DFF1, anticorps ICAD, anticorps A330085O09Rik, anticorps DFF35, anticorps Dff45, anticorps ICAD-L, anticorps ICAD-S, anticorps DFFA, anticorps zgc:92229, anticorps DNA fragmentation factor subunit alpha, anticorps DNA fragmentation factor, alpha subunit, anticorps DNA fragmentation factor, 45kDa, alpha polypeptide, anticorps DNA fragmentation factor, alpha polypeptide, anticorps DFFA, anticorps Dffa, anticorps dffa
    Sujet
    Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DFFA,DFF-45,DFF1,ICAD,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Death Receptor Signaling Pathway,Endocrine & Metabolism,DFFA
    Poids moléculaire
    29 kDa/36 kDa
    ID gène
    1676
    UniProt
    O00273
    Pathways
    Apoptose, Caspase Cascade in Apoptosis
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