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Granulin anticorps (AA 281-336)

GRN Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6141431
  • Antigène Voir toutes Granulin (GRN) Anticorps
    Granulin (GRN)
    Épitope
    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-336
    Reactivité
    • 51
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 9
    • 5
    • 2
    • 1
    Lapin
    Clonalité
    • 48
    • 11
    Polyclonal
    Conjugué
    • 35
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Granulin est non-conjugé
    Application
    • 52
    • 19
    • 17
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    DVKCDMEVSC PDGYTCCRLQ SGAWGCCPFT QAVCCEDHIH CCPAGFTCDT QKGTCE
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 281-336 of human Granulin (NP_002078.1).
    Isotype
    IgG
    Top Product
    Discover our top product GRN Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Granulin (GRN)
    Autre désignation
    GRN (GRN Produits)
    Synonymes
    anticorps GRN, anticorps grn, anticorps wu:fb11g12, anticorps wu:fj18f05, anticorps MGC53354, anticorps DKFZp459H066, anticorps CLN11, anticorps GEP, anticorps GP88, anticorps PCDGF, anticorps PEPI, anticorps PGRN, anticorps epithelin, anticorps acrogranin, anticorps granulin precursor, anticorps granulin a, anticorps Granulins, anticorps granulin L homeolog, anticorps granulin, anticorps GRN, anticorps grna, anticorps grn, anticorps grn.L, anticorps granulin, anticorps ORF1 granulin, anticorps Grn
    Sujet
    Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.,GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN,granulins,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,GRN
    Poids moléculaire
    44 kDa/46 kDa/63 kDa
    ID gène
    2896
    UniProt
    P28799
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