GTF2H1 anticorps (AA 1-425)

N° du produit ABIN6141498

Détail du produit anti-GTF2H1 anticorps

Antigène: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Épitope: AA 1-425

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2H1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MATSSEEVLL IVKKVRQKKQ DGALYLMAER IAWAPEGKDR FTISHMYADI KCQKISPEGK AKIQLQLVLH AGDTTNFHFS NESTAVKERD AVKDLLQQLL PKFKRKANKE LEEKNRMLQE DPVLFQLYKD LVVSQVISAE EFWANRLNVN ATDSSSTSNH KQDVGISAAF LADVRPQTDG CNGLRYNLTS DIIESIFRTY PAVKMKYAEN VPHNMTEKEF WTRFFQSHYF HRDRLNTGSK DLFAECAKID EKGLKTMVSL GVKNPLLDLT ALEDKPLDEG YGISSVPSAS NSKSIKENSN AAIIKRFNHH SAMVLAAGLR KQEAQNEQTS EPSNMDGNSG DADCFQPAVK RAKLQESIEY EDLGKNNSVK TIALNLKKSD RYYHGPTPIQ SLQYATSQDI INSFQSIRQE MEAYTPKLTQ VLSSS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human GTF2H1 (NP_001135779.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GTF2H1

Antigène: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Autre désignation: GTF2H1 (GTF2H1 Produits)

Synonymes: anticorps 62kDa, anticorps AW743425, anticorps AW822074, anticorps BTF2 p62, anticorps C77871, anticorps p62, anticorps GTF2H1, anticorps BTF2, anticorps P62, anticorps TFB1, anticorps TFIIH, anticorps gtf2h1, anticorps MGC53309, anticorps btf2, anticorps tfiih, anticorps CG8151, anticorps Dmel\\CG8151, anticorps Dmp62, anticorps TfBl, anticorps l(2)06949, anticorps l(2)06950, anticorps zgc:92126, anticorps general transcription factor IIH subunit 1, anticorps general transcription factor II H, polypeptide 1, anticorps general transcription factor IIH subunit 1 L homeolog, anticorps Transcription factor B1, anticorps general transcription factor IIH, polypeptide 1, anticorps GTF2H1, anticorps Gtf2h1, anticorps gtf2h1.L, anticorps gtf2h1, anticorps Tfb1

Sujet: Component of the general transcription and DNA repair factor IIH (TFIIH core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.,GTF2H1,BTF2,P62,TFB1,TFIIH,Epigenetics & Nuclear Signaling,GTF2H1

Poids moléculaire: 48 kDa/62 kDa

ID gène: 2965

UniProt: P32780

Pathways: Réparation de l'ADN