HERPUD1 anticorps (AA 1-240)

N° du produit ABIN6141721

Détail du produit anti-HERPUD1 anticorps

Antigène: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Épitope: AA 1-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HERPUD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MESETEPEPV TLLVKSPNQR HRDLELSGDR GWSVGHLKAH LSRVYPERPR PEDQRLIYSG KLLLDHQCLR DLLPKQEKRH VLHLVCNVKS PSKMPEINAK VAESTEEPAG SNRGQYPEDS SSDGLRQREV LRNLSSPGWE NISRPEAAQQ AFQGLGPGFS GYTPYGWLQL SWFQQIYARQ YYMQYLAATA ASGAFVPPPS AQEIPVVSAP APAPIHNQFP AENQPANQNA APQVVVNPGA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HERPUD1 (NP_055500.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HERPUD1

Antigène: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Autre désignation: HERPUD1 (HERPUD1 Produits)

Synonymes: anticorps herpud1-a, anticorps herp, anticorps herpud1, anticorps mif1, anticorps sup, anticorps HERPUD1, anticorps zgc:114134, anticorps HERP, anticorps Mif1, anticorps SUP, anticorps Herp, anticorps Mifl, anticorps Sup, anticorps homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog, anticorps homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog, anticorps homocysteine inducible ER protein with ubiquitin like domain 1, anticorps homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, anticorps herpud1.S, anticorps herpud1.L, anticorps herpud1, anticorps HERPUD1, anticorps Herpud1

Sujet: The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.,HERPUD1,HERP,Mif1,SUP,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,HERPUD1

Poids moléculaire: 26 kDa/40 kDa/43 kDa

ID gène: 9709

UniProt: Q15011

Pathways: ER-Nucleus Signaling