IL12RB2 anticorps (AA 420-620)

N° du produit ABIN6142303

Détail du produit anti-IL12RB2 anticorps

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Épitope: AA 420-620

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12RB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GLLAPRQVSA NSEGMDNILV TWQPPRKDPS AVQEYVVEWR ELHPGGDTQV PLNWLRSRPY NVSALISENI KSYICYEIRV YALSGDQGGC SSILGNSKHK APLSGPHINA ITEEKGSILI SWNSIPVQEQ MGCLLHYRIY WKERDSNSQP QLCEIPYRVS QNSHPINSLQ PRVTYVLWMT ALTAAGESSH GNEREFCLQG K

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 420-620 of human IL12RB2 (NP_001550.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IL12RB2

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Autre désignation: IL12RB2 (IL12RB2 Produits)

Synonymes: anticorps IL12RB2, anticorps A930027I18Rik, anticorps IL-12RB2, anticorps Ifnm, anticorps interleukin 12 receptor subunit beta 2, anticorps interleukin 12 receptor, beta 2, anticorps IL12RB2, anticorps Il12rb2

Sujet: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.,IL12RB2,Cancer,Tumor immunology,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL12RB2

Poids moléculaire: 74 kDa/87 kDa/97 kDa

ID gène: 3595

UniProt: Q99665

Pathways: Signalistation JAK/STAT