Integrin beta 7 anticorps (AA 1-140)

N° du produit ABIN6142589

Détail du produit anti-Integrin beta 7 anticorps

Antigène: Integrin beta 7 (ITGB7)

Épitope: AA 1-140

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 7 est non-conjugé

Application: Western Blotting (WB)

Séquence: MVALPMVLVL LLVLSRGESE LDAKIPSTGD ATEWRNPHLS MLGSCQPAPS CQKCILSHPS CAWCKQLNFT ASGEAEARRC ARREELLARG CPLEELEEPR GQQEVLQDQP LSQGARGEGA TQLAPQRVRV TLRPGEPQQL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ITGB7 (NP_000880.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: ITGB7 (ITGB7 Produits)

Synonymes: anticorps Ly69, anticorps integrin beta 7, anticorps integrin subunit beta 7, anticorps integrin, beta 7, anticorps Itgb7, anticorps ITGB7

Sujet: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,ITGB7,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Stem Cells,Hematopoietic Progenitors,ITGB7

Poids moléculaire: 71 kDa/86 kDa

ID gène: 3695

UniProt: P26010

Pathways: Integrin Complex