KHDRBS2 anticorps (C-Term)

N° du produit ABIN6142831

Détail du produit anti-KHDRBS2 anticorps

Antigène: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDRBS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TAPSRGRGGA IPPPPPPGRG VLTPRGSTVT RGALPVPPVA RGVPTPRARG APTVPGYRAP PPPAHEAYEE YGYDDGYGGE YDDQTYETYD NSYATQTQSV PEYYDYGHGV SEDAYDSYAP EEWATTRSSL KAPPQRSARG GYREHPYGRY

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human KHDRBS2 (NP_689901.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:100 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KHDRBS2

Antigène: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Autre désignation: KHDRBS2 (KHDRBS2 Produits)

Synonymes: anticorps slm1, anticorps slm-1, anticorps MGC145973, anticorps ba535f17.1, anticorps zgc:153588, anticorps SLM-1, anticorps SLM1, anticorps bA535F17.1, anticorps 6330586C16Rik, anticorps Slim1, anticorps Slm1, anticorps KH RNA binding domain containing, signal transduction associated 2, anticorps KH domain containing, RNA binding, signal transduction associated 2, anticorps KHDRBS2, anticorps khdrbs2, anticorps Khdrbs2

Sujet: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A and poly(U homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4 involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.,KHDRBS2,SLM-1,SLM1,Epigenetics & Nuclear Signaling,KHDRBS2

Poids moléculaire: 38 kDa

ID gène: 202559

UniProt: Q5VWX1