Kallikrein 6 anticorps (C-Term)

N° du produit ABIN6142958

Détail du produit anti-Kallikrein 6 anticorps

Antigène: Kallikrein 6 (KLK6)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 6 est non-conjugé

Application: Western Blotting (WB)

Séquence: AASHDQDIML LRLARPAKLS ELIQPLPLER DCSANTTSCH ILGWGKTADG DFPDTIQCAY IHLVSREECE HAYPGQITQN MLCAGDEKYG KDSCQGDSGG PLVCGDHLRG LVSWGNIPCG SKEKPGVYTN VCRYTNWIQK TIQAK

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human KLK6 (NP_002765.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Kallikrein 6

Antigène: Kallikrein 6 (KLK6)

Autre désignation: KLK6 (KLK6 Produits)

Synonymes: anticorps Bssp, anticorps Klk7, anticorps PRSS18, anticorps PRSS9, anticorps SP59, anticorps hK6, anticorps Prss9, anticorps AI849898, anticorps BSP, anticorps Klk29, anticorps MSP, anticorps Prss18, anticorps neurosin, anticorps kallikrein related peptidase 6, anticorps kallikrein related-peptidase 6, anticorps kallikrein-6, anticorps KLK6, anticorps Klk6, anticorps LOC100716801

Sujet: This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,KLK6,Bssp,Klk7,PRSS18,PRSS9,SP59,hK6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,KLK6

Poids moléculaire: 4 kDa/15 kDa/26 kDa

ID gène: 5653

UniProt: Q92876

Pathways: Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling