LILRB4 anticorps (AA 22-259)

N° du produit ABIN6143221

Détail du produit anti-LILRB4 anticorps

Antigène: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Épitope: AA 22-259

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LILRB4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: QAGPLPKPTL WAEPGSVISW GNSVTIWCQG TLEAREYRLD KEESPAPWDR QNPLEPKNKA RFSIPSMTED YAGRYRCYYR SPVGWSQPSD PLELVMTGAY SKPTLSALPS PLVTSGKSVT LLCQSRSPMD TFLLIKERAA HPLLHLRSEH GAQQHQAEFP MSPVTSVHGG TYRCFSSHGF SHYLLSHPSD PLELIVSGSL EGPRPSPTRS VSTAAGPEDQ PLMPTGSVPH SGLRRHWE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 22-259 of human LILRB4 (NP_001265355.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LILRB4

Antigène: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Autre désignation: LILRB4 (LILRB4 Produits)

Synonymes: anticorps CD85K, anticorps ILT-3, anticorps ILT3, anticorps LIR-5, anticorps LIR5, anticorps Gp49b, anticorps HM18, anticorps gp49, anticorps leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4, anticorps leukocyte immunoglobulin like receptor B4, anticorps leukocyte immunoglobulin-like receptor, subfamily B, member 4A, anticorps LILRB4, anticorps Lilrb4a

Sujet: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.,LILRB4,CD85K,ILT-3,ILT3,LIR-5,LIR5,Epigenetics & Nuclear Signaling,Immunology & Inflammation,CD markers,Cardiovascular,Blood,Blood Cell Antigens,LILRB4

Poids moléculaire: 49 kDa

ID gène: 11006

UniProt: Q8NHJ6