MAN2B1 anticorps (AA 640-850)

N° du produit ABIN6143456

Détail du produit anti-MAN2B1 anticorps

Antigène: MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))

Épitope: AA 640-850

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAN2B1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TFFWYNASIG DNESDQASGA YIFRPNQQKP LPVSRWAQIH LVKTPLVQEV HQNFSAWCSQ VVRLYPGQRH LELEWSVGPI PVGDTWGKEV ISRFDTPLET KGRFYTDSNG REILERRRDY RPTWKLNQTE PVAGNYYPVN TRIYITDGNM QLTVLTDRSQ GGSSLRDGSL ELMVHRRLLK DDGRGVSEPL MENGSGAWVR GRHLVLLDTA Q

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 640-850 of human MAN2B1 (NP_000519.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MAN2B1

Antigène: MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))

Autre désignation: MAN2B1 (MAN2B1 Produits)

Synonymes: anticorps AW107687, anticorps LAMAN, anticorps Laman, anticorps Manb, anticorps MANB, anticorps mannosidase alpha class 2B member 1, anticorps mannosidase, alpha, class 2B, member 1, anticorps mannosidase 2, alpha B1, anticorps MAN2B1, anticorps man2b1, anticorps Man2b1

Sujet: This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MAN2B1,LAMAN,MANB,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,MAN2B1

Poids moléculaire: 113 kDa

ID gène: 4125

UniProt: O00754