MARK1 anticorps (AA 560-700)

N° du produit ABIN6143561

Détail du produit anti-MARK1 anticorps

Antigène: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Épitope: AA 560-700

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: HPIKVTLPTI KDGSEAYRPG TTQRVPAASP SAHSISTATP DRTRFPRGSS SRSTFHGEQL RERRSVAYNG PPASPSHETG AFAHARRGTS TGIISKITSK FVRRDPSEGE ASGRTDTSRS TSGEPKERDK EEGKDSKPRS L

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 560-700 of human MARK1 (NP_061120.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MARK1

Antigène: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Autre désignation: MARK1 (MARK1 Produits)

Synonymes: anticorps MGC80341, anticorps MARK1, anticorps AW491150, anticorps B930025N23Rik, anticorps Emk3, anticorps Par-1c, anticorps mKIAA1477, anticorps mPar-1c, anticorps MARK, anticorps Par1c, anticorps MAP/microtubule affinity-regulating kinase 1 S homeolog, anticorps microtubule affinity regulating kinase 1, anticorps MAP/microtubule affinity-regulating kinase 1, anticorps MAP/microtubule affinity regulating kinase 1, anticorps mark1.S, anticorps MARK1, anticorps mark1, anticorps Mark1

Sujet: Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3.,MARK1,MARK,Par-1c,Par1c,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,MARK1

Poids moléculaire: 72 kDa/84 kDa/89 kDa

ID gène: 4139

UniProt: Q9P0L2

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2