MATK anticorps (AA 352-466)

N° du produit ABIN6143578

Détail du produit anti-MATK anticorps

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Épitope: AA 352-466

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PEALKHGKFT SKSDVWSFGV LLWEVFSYGR APYPKMSLKE VSEAVEKGYR MEPPEGCPGP VHVLMSSCWE AEPARRPPFR KLAEKLAREL RSAGAPASVS GQDADGSTSP RSQEP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: MATK (MATK Produits)

Synonymes: anticorps si:ch211-63j24.2, anticorps CHK, anticorps CTK, anticorps HHYLTK, anticorps HYL, anticorps HYLTK, anticorps Lsk, anticorps Ntk, anticorps Batk, anticorps megakaryocyte-associated tyrosine kinase, anticorps zinc finger RNA binding protein 2, anticorps matk, anticorps MATK, anticorps Matk, anticorps ZFR2

Sujet: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.,MATK,CHK,CTK,HHYLTK,HYL,HYLTK,Lsk,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,MATK

Poids moléculaire: 51 kDa/56 kDa

ID gène: 4145

UniProt: P42679