MBTPS1 anticorps (AA 803-1052)

N° du produit ABIN6143605

Détail du produit anti-MBTPS1 anticorps

Antigène: MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))

Épitope: AA 803-1052

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBTPS1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: ITQTFKDQGL EVLKQETAVV ENVPILGLYQ IPAEGGGRIV LYGDSNCLDD SHRQKDCFWL LDALLQYTSY GVTPPSLSHS GNRQRPPSGA GSVTPERMEG NHLHRYSKVL EAHLGDPKPR PLPACPRLSW AKPQPLNETA PSNLWKHQKL LSIDLDKVVL PNFRSNRPQV RPLSPGESGA WDIPGGIMPG RYNQEVGQTI PVFAFLGAMV VLAFFVVQIN KAKSRPKRRK PRVKRPQLMQ QVHPPKTPSV

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1).

Isotype: IgG

Information d'application

Indications d'application: IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MBTPS1

Antigène: MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))

Autre désignation: MBTPS1 (MBTPS1 Produits)

Synonymes: anticorps PCSK8, anticorps S1P, anticorps SKI-1, anticorps 0610038M03Rik, anticorps AV003995, anticorps Ski1, anticorps mKIAA0091, anticorps S1p, anticorps Ski-1, anticorps membrane bound transcription factor peptidase, site 1, anticorps membrane-bound transcription factor peptidase, site 1, anticorps MBTPS1, anticorps Mbtps1

Sujet: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.,MBTPS1,PCSK8,S1P,SKI-1,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Lipid Metabolism,MBTPS1

Poids moléculaire: 117 kDa

ID gène: 8720

UniProt: Q14703

Pathways: ER-Nucleus Signaling