MRGPRX1 anticorps (AA 263-322)

N° du produit ABIN6143996

Détail du produit anti-MRGPRX1 anticorps

Antigène: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Épitope: AA 263-322

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRX1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LNSSANPIIY FFVGSFRQRQ NRQNLKLVLQ RALQDASEVD EGGGQLPEEI LELSGSRLEQ

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 263-322 of human MRGPRX1 (NP_671732.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MRGPRX1

Antigène: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Autre désignation: MRGPRX1 (MRGPRX1 Produits)

Synonymes: anticorps GPCR, anticorps MRGX1, anticorps SNSR4, anticorps MrgC11, anticorps Mrgprc11, anticorps Snsr1, anticorps MAS related GPR family member X1, anticorps MAS-related GPR, member X1, anticorps MRGPRX1, anticorps Mrgprx1

Sujet: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22 and BAM (8-22(PubMed:26582731. BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alphaq proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.,MRGPRX1,GPCR,MGRG2,MRGX1,SNSR4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),MRGPRX1

Poids moléculaire: 36 kDa

ID gène: 259249

UniProt: Q96LB2