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MTOR anticorps (AA 2388-2487)

mTOR Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6144169
  • Antigène Voir toutes MTOR (mTOR) Anticorps
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    Épitope
    • 34
    • 28
    • 23
    • 15
    • 12
    • 11
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2388-2487
    Reactivité
    • 213
    • 140
    • 121
    • 23
    • 17
    • 12
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 193
    • 16
    • 2
    • 2
    Lapin
    Clonalité
    • 173
    • 39
    Polyclonal
    Conjugué
    • 109
    • 11
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MTOR est non-conjugé
    Application
    • 147
    • 65
    • 63
    • 52
    • 52
    • 43
    • 36
    • 35
    • 17
    • 17
    • 12
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    EVTGLDGNYR ITCHTVMEVL REHKDSVMAV LEAFVYDPLL NWRLMDTNTK GNKRSRTRTD SYSAGQSVEI LDGVELGEPA HKKTGTTVPE SIHSFIGDGL
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 2388-2487 of human mTOR (NP_004949.1).
    Isotype
    IgG
    Top Product
    Discover our top product mTOR Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Xie, Liu, Chen, Xu, Zhan, Yang, Li, Zhou: "Umbilical cord-derived mesenchymal stem cells alleviated inflammation and inhibited apoptosis in interstitial cystitis via AKT/mTOR signaling pathway." dans: Biochemical and biophysical research communications, Vol. 495, Issue 1, pp. 546-552, (2017) (PubMed).

  • Antigène
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    Autre désignation
    mTOR (mTOR Produits)
    Synonymes
    anticorps FRAP1, anticorps FRAP, anticorps FRAP2, anticorps RAFT1, anticorps RAPT1, anticorps 2610315D21Rik, anticorps AI327068, anticorps Frap1, anticorps flat, anticorps frap1, anticorps tor, anticorps wu:fc22h08, anticorps mechanistic target of rapamycin kinase, anticorps mechanistic target of rapamycin, anticorps mechanistic target of rapamycin (serine/threonine kinase), anticorps MTOR, anticorps Mtor, anticorps mtor
    Sujet
    The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.,FRAP,FRAP1,FRAP2,RAFT1,RAPT1,SKS,mTOR,MTOR,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,Cell cycle inhibitors,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Heart,Cardiogenesis,Regulators,mTOR
    Poids moléculaire
    288 kDa
    ID gène
    2475
    UniProt
    P42345
    Pathways
    Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, L'effet Warburg
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