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IL1R1 anticorps (Extracellular Domain)

IL1R1 Reactivité: Humain IHC (p), RIA, IF, EIA Hôte: Souris Monoclonal 40101 unconjugated
N° du produit ABIN614470
  • Antigène Voir toutes IL1R1 Anticorps
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Épitope
    • 28
    • 17
    • 16
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivité
    • 119
    • 68
    • 53
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 113
    • 13
    • 10
    • 5
    • 2
    • 1
    Souris
    Clonalité
    • 120
    • 24
    Monoclonal
    Conjugué
    • 61
    • 17
    • 11
    • 8
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp IL1R1 est non-conjugé
    Application
    • 124
    • 65
    • 47
    • 39
    • 16
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    These antibodies react with cell surface and soluble human IL-1 receptor. Specific epitopes are unknown, but they do partially inhibit (30-50 %) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for Human IL-2 or IL-4.
    Purification
    Affinity chromatography on Protein G
    Immunogène
    Extracellular domain of the type I Human IL-1 receptor.
    Clone
    40101
    Isotype
    IgG2b
    Top Product
    Discover our top product IL1R1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Autre désignation
    CD121a / IL1R1 (IL1R1 Produits)
    Synonymes
    anticorps CD121A, anticorps D2S1473, anticorps IL-1R-alpha, anticorps IL1R, anticorps IL1RA, anticorps P80, anticorps CD121a, anticorps CD121b, anticorps IL-iR, anticorps Il1r-1, anticorps DER4, anticorps Fit-1, anticorps Ly84, anticorps ST2L, anticorps St2, anticorps St2-rs1, anticorps T1, anticorps T1/ST2, anticorps interleukin 1 receptor type 1, anticorps interleukin 1 receptor, type I, anticorps interleukin 1 receptor-like 1, anticorps IL1R1, anticorps Il1r1, anticorps Il1rl1
    Sujet
    IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.Synonyms: IL-1R-alpha, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I
    ID gène
    3554
    NCBI Accession
    NP_000868
    UniProt
    P14778
    Pathways
    Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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