NOTCH4 anticorps (AA 1824-2003)

N° du produit ABIN6144740

Détail du produit anti-NOTCH4 anticorps

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Épitope: AA 1824-2003

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: PPEARHKATP GREAGPFPRA RTVSVSVPPH GGGALPRCRT LSAGAGPRGG GACLQARTWS VDLAARGGGA YSHCRSLSGV GAGGGPTPRG RRFSAGMRGP RPNPAIMRGR YGVAAGRGGR VSTDDWPCDW VALGACGSAS NIPIPPPCLT PSPERGSPQL DCGPPALQEM PINQGGEGKK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1824-2003 of human NOTCH4 (NP_004548.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NOTCH4

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Autre désignation: NOTCH4 (NOTCH4 Produits)

Sujet: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,NOTCH4,INT3,notch 4,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,Cardiovascular,Angiogenesis,Heart,Cardiogenesis,NOTCH4

Poids moléculaire: 39 kDa/61 kDa/209 kDa

ID gène: 4855

UniProt: Q99466

Pathways: Signalisation Notch