NUDT15 anticorps (AA 1-164)

N° du produit ABIN6144931

Détail du produit anti-NUDT15 anticorps

Antigène: NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

Épitope: AA 1-164

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUDT15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MTASAQPRGR RPGVGVGVVV TSCKHPRCVL LGKRKGSVGA GSFQLPGGHL EFGETWEECA QRETWEEAAL HLKNVHFASV VNSFIEKENY HYVTILMKGE VDVTHDSEPK NVEPEKNESW EWVPWEELPP LDQLFWGLRC LKEQGYDPFK EDLNHLVGYK GNHL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 (NP_060753.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-NUDT15 (ABIN6144931)

Li, Yang, Tian, Li, Cui, Chen, Deng, Chen, Hayakawa, Sekiguchi, Cai: "MutT-related proteins are novel progression and prognostic markers for colorectal cancer." dans: Oncotarget, Vol. 8, Issue 62, pp. 105714-105726, (2017) (PubMed).

Détails sur NUDT15

Antigène: NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

Autre désignation: NUDT15 (NUDT15 Produits)

Synonymes: anticorps MTH2, anticorps RP11-90M2.1, anticorps 6530403O17, anticorps A730068G11Rik, anticorps nudix hydrolase 15, anticorps nudix (nucleoside diphosphate linked moiety X)-type motif 15, anticorps NUDT15, anticorps Nudt15

Sujet: This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.,NUDT15,MTH2,NUDT15D,Epigenetics & Nuclear Signaling,NUDT15

Poids moléculaire: 18 kDa

ID gène: 55270

UniProt: Q9NV35