P2RX7 anticorps (AA 47-334)

N° du produit ABIN6145122

Détail du produit anti-P2RX7 anticorps

Antigène: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Épitope: AA 47-334

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RX7 est non-conjugé

Application: Western Blotting (WB)

Séquence: SDKLYQRKEP VISSVHTKVK GIAEVKEEIV ENGVKKLVHS VFDTADYTFP LQGNSFFVMT NFLKTEGQEQ RLCPEYPTRR TLCSSDRGCK KGWMDPQSKG IQTGRCVVYE GNQKTCEVSA WCPIEAVEEA PRPALLNSAE NFTVLIKNNI DFPGHNYTTR NILPGLNITC TFHKTQNPQC PIFRLGDIFR ETGDNFSDVA IQGGIMGIEI YWDCNLDRWF HHCRPKYSFR RLDDKTTNVS LYPGYNFRYA KYYKENNVEK RTLIKVFGIR FDILVFGTGG KFDIIQLV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 47-334 of human P2RX7 (NP_002553.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur P2RX7

Antigène: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Autre désignation: P2RX7 (P2RX7 Produits)

Synonymes: anticorps p2xr7, anticorps P2RX7, anticorps P2X7, anticorps AI467586, anticorps P2X(7), anticorps P2X7R, anticorps p2x7, anticorps purinergic receptor P2X 7, anticorps purinergic receptor P2X, ligand-gated ion channel, 7, anticorps P2X purinoceptor 7, anticorps P2RX7, anticorps p2rx7, anticorps LOC100458463, anticorps P2rx7

Sujet: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.,P2RX7,P2X7,Neuroscience,P2RX7

Poids moléculaire: 14 kDa/31 kDa/35 kDa/41 kDa/49 kDa/58 kDa/68 kDa

ID gène: 5027

UniProt: Q99572

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis