PADI1 anticorps (AA 1-260)

N° du produit ABIN6145161

Détail du produit anti-PADI1 anticorps

Antigène: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Épitope: AA 1-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PADI1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAPKRVVQLS LKMPTHAVCV VGVEAHVDIH SDVPKGANSF RVSGSSGVEV FMVYNRTRVK EPIGKARWPL DTDADMVVSV GTASKELKDF KVRVSYFGEQ EDQALGRSVL YLTGVDISLE VDTGRTGKVK RSQGDKKTWR WGPEGYGAIL LVNCDRDNHR SAEPDLTHSW LMSLADLQDM SPMLLSCNGP DKLFDSHKLV LNVPFSDSKR VRVFCARGGN SLSDYKQVLG PQCLSYEVER QPGEQEIKFY VEGLTFPDAD

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PADI1 (NP_037490.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PADI1

Antigène: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Autre désignation: PADI1 (PADI1 Produits)

Synonymes: anticorps HPAD10, anticorps PAD1, anticorps PDI, anticorps PDI1, anticorps AV236283, anticorps Pdi1, anticorps peptidyl arginine deiminase 1, anticorps peptidyl arginine deiminase, type I, anticorps PADI1, anticorps Padi1

Sujet: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.,PADI1,HPAD10,PAD1,PDI,PDI1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PADI1

Poids moléculaire: 74 kDa

ID gène: 29943

UniProt: Q9ULC6