PLSCR1 anticorps (AA 1-318)

N° du produit ABIN6145796

Détail du produit anti-PLSCR1 anticorps

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Épitope: AA 1-318

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLSCR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MDKQNSQMNA SHPETNLPVG YPPQYPPTAF QGPPGYSGYP GPQVSYPPPP AGHSGPGPAG FPVPNQPVYN QPVYNQPVGA AGVPWMPAPQ PPLNCPPGLE YLSQIDQILI HQQIELLEVL TGFETNNKYE IKNSFGQRVY FAAEDTDCCT RNCCGPSRPF TLRIIDNMGQ EVITLERPLR CSSCCCPCCL QEIEIQAPPG VPIGYVIQTW HPCLPKFTIQ NEKREDVLKI SGPCVVCSCC GDVDFEIKSL DEQCVVGKIS KHWTGILREA FTDADNFGIQ FPLDLDVKMK AVMIGACFLI DFMFFESTGS QEQKSGVW

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human Phospholipid Scramblase 1 (Phospholipid Scramblase 1 (PLSCR1)) (NP_066928.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLSCR1

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Autre désignation: PLSCR1 (PLSCR1 Produits)

Synonymes: anticorps mmtra1b, anticorps MGC84969, anticorps PLSCR1, anticorps MGC148322, anticorps MMTRA1B, anticorps MmTRA1a, anticorps MmTRA1b, anticorps Nor1, anticorps Tra1, anticorps Tra1a, anticorps Tra1b, anticorps Tras1, anticorps Tras2, anticorps PLSCR2, anticorps phospholipid scramblase 1 L homeolog, anticorps phospholipid scramblase 1, anticorps plscr1.L, anticorps PLS1, anticorps PVX_111580, anticorps PLSCR1, anticorps plscr1, anticorps Plscr1, anticorps LOC100712949, anticorps PLSCR2, anticorps LOC100341366, anticorps LOC611500

Sujet: Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with TRPC5 (By similarity. Also exhibits magnesium-dependent nuclease activity against double-stranded DNA and RNA but not single-stranded DNA and can enhance DNA decatenation mediated by TOP2A. Negatively regulates FcR-mediated phagocytosis in differentiated macrophages. May contribute to cytokine-regulated cell proliferation and differentiation (By similarity. May play a role in the antiviral response of interferon (IFN by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. Acts as an attachment receptor for HCV.,PLSCR1,MMTRA1B,Signal Transduction,Neuroscience,Calcium Signaling,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,PLSCR1

Poids moléculaire: 26 kDa/35 kDa

ID gène: 5359

UniProt: O15162

Pathways: Cellular Response to Molecule of Bacterial Origin