Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

NOXA anticorps (AA 1-54)

PMAIP1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6145810
  • Antigène Voir toutes NOXA (PMAIP1) Anticorps
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    Épitope
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-54
    Reactivité
    • 33
    • 7
    • 3
    Humain
    Hôte
    • 28
    • 6
    • 1
    • 1
    Lapin
    Clonalité
    • 21
    • 15
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp NOXA est non-conjugé
    Application
    • 16
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MPGKKARKNA QPSPARAPAE LEVECATQLR RFGDKLNFRQ KLLNLISKLF CSGT
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 1-54 of human PMAIP1 (NP_066950.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    Autre désignation
    PMAIP1 (PMAIP1 Produits)
    Synonymes
    anticorps TN3, anticorps PMAIP1, anticorps zgc:162379, anticorps APR, anticorps NOXA, anticorps Noxa, anticorps phorbol-12-myristate-13-acetate-induced protein 1, anticorps PMAIP1, anticorps pmaip1, anticorps Pmaip1
    Sujet
    Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.,PMAIP1,APR,NOXA,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Endocrine & Metabolism,PMAIP1
    Poids moléculaire
    6 kDa/14 kDa
    ID gène
    5366
    UniProt
    Q13794
    Pathways
    Signalisation p53, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Vous êtes ici:
Support technique