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PTTG1 anticorps (AA 1-202)

PTTG1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6146486
  • Antigène Voir toutes PTTG1 Anticorps
    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
    Épitope
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-202
    Reactivité
    • 46
    • 12
    • 11
    • 1
    Humain
    Hôte
    • 35
    • 11
    • 1
    Lapin
    Clonalité
    • 29
    • 18
    Polyclonal
    Conjugué
    • 29
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp PTTG1 est non-conjugé
    Application
    • 22
    • 18
    • 11
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MATLIYVDKE NGEPGTRVVA KDGLKLGSGP SIKALDGRSQ VSTPRFGKTF DAPPALPKAT RKALGTVNRA TEKSVKTKGP LKQKQPSFSA KKMTEKTVKA KSSVPASDDA YPEIEKFFPF NPLDFESFDL PEEHQIAHLP LSGVPLMILD EERELEKLFQ LGPPSPVKMP SPPWESNLLQ SPSSILSTLD VELPPVCCDI DI
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human PTTG1 (NP_001269311.1).
    Isotype
    IgG
    Top Product
    Discover our top product PTTG1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
    Autre désignation
    PTTG1 (PTTG1 Produits)
    Synonymes
    anticorps EAP1, anticorps HPTTG, anticorps PTTG, anticorps TUTR1, anticorps PTTG1, anticorps securin, anticorps AW555095, anticorps C87862, anticorps Pttg, anticorps Pttg3, anticorps Securin, anticorps Protein Cut2, anticorps pituitary tumor-transforming 1, anticorps pituitary tumor-transforming gene 1, anticorps securin, sister chromatid separation inhibitor, anticorps PTTG1, anticorps Pttg1, anticorps cut2
    Sujet
    The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene.,PTTG1,EAP1,HPTTG,PTTG,TUTR1,securin,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,PTTG1
    Poids moléculaire
    22 kDa
    ID gène
    9232
    UniProt
    O95997
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