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PYGL anticorps (AA 1-280)

PYGL Reactivité: Humain WB, IHC, IP, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6146525
  • Antigène Voir toutes PYGL Anticorps
    PYGL (phosphorylase, Glycogen, Liver (PYGL))
    Épitope
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-280
    Reactivité
    • 47
    • 20
    • 13
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 2
    Lapin
    Clonalité
    • 54
    • 2
    Polyclonal
    Conjugué
    • 19
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PYGL est non-conjugé
    Application
    • 28
    • 17
    • 13
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Séquence
    MAKPLTDQEK RRQISIRGIV GVENVAELKK SFNRHLHFTL VKDRNVATTR DYYFALAHTV RDHLVGRWIR TQQHYYDKCP KRVYYLSLEF YMGRTLQNTM INLGLQNACD EAIYQLGLDI EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEYGIFNQK IRDGWQVEEA DDWLRYGNPW EKSRPEFMLP VHFYGKVEHT NTGTKWIDTQ VVLALPYDTP VPGYMNNTVN TMRLWSARAP NDFNLRDFNV GDYIQAVLDR NLAENISRVL
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PYGL (NP_002854.3).
    Isotype
    IgG
    Top Product
    Discover our top product PYGL Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PYGL (phosphorylase, Glycogen, Liver (PYGL))
    Autre désignation
    PYGL (PYGL Produits)
    Synonymes
    anticorps zgc:66314, anticorps GSD6, anticorps glycogen phosphorylase L, anticorps phosphorylase, glycogen, liver, anticorps phosphorylase, glycogen, liver S homeolog, anticorps liver glycogen phosphorylase, anticorps PYGL, anticorps pygl, anticorps pygl.S, anticorps Pygl
    Sujet
    This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.,PYGL,GSD6,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,PYGL
    Poids moléculaire
    93 kDa/97 kDa
    ID gène
    5836
    UniProt
    P06737
    Pathways
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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