Souris anti-Humain IgG (Fc Region) Anticorps

Détails pour le produit réf. ABIN614786, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
Fc Region
4782
2534
1960
1067
1022
861
306
292
35
34
31
8
7
7
3
3
2
2
1
1
1
1
1
Reactivité
Humain
2896
2761
2297
1676
1453
790
626
454
395
387
359
346
298
296
221
138
135
130
41
31
29
24
16
11
10
8
7
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
Hôte
Souris
6786
4909
1788
922
609
392
91
68
55
18
8
5
5
5
2
1
1
Clonalité (Clone)
Monoclonal ()
Application
Immunofluorescence (IF)
Options
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Supplier Product No.
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Immunogène Fusion protein of human IgG Fc fragment
Clone EM-07
Isotype IgG1
Réactivité croisée (Details) Species reactivity (tested):Human.
Purification Protein A affinity Chromatography
Pureté > 95 % pure by SDS-PAGE
Sujet Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.Synonyms: Human Immunoglobulin G
Poids moléculaire 150 kDa
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.4, 15 mM Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for Mouse anti-Human IgG (Fc Region) antibody (ABIN614786) Mouse anti-Human IgG (Fc Region) antibody
Background publications Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." dans: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." dans: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." dans: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).

Franklin: "Structure and function of immunoglobulins." dans: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).