GLUT4 anticorps (C-Term)

N° du produit ABIN6147963

Détail du produit anti-GLUT4 anticorps

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: GPIPWFIVAE LFSQGPRPAA MAVAGFSNWT SNFIIGMGFQ YVAEAMGPYV FLLFAVLLLG FFIFTFLRVP ETRGRTFDQI SAAFHRTPSL LEQEVKPSTE LEYLGPDEND

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human GLUT4 (NP_001033.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-GLUT4 (ABIN6147963)

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." dans: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Détails sur GLUT4

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Autre désignation: SLC2A4 (SLC2A4 Produits)

Synonymes: anticorps GLUT4, anticorps Glut-4, anticorps Glut4, anticorps glut4, anticorps slc2a4, anticorps SLC2A4, anticorps solute carrier family 2 member 4, anticorps solute carrier family 2 (facilitated glucose transporter), member 4, anticorps solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog, anticorps SLC2A4, anticorps Slc2a4, anticorps GLUT4, anticorps slc2a4.L

Sujet: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).,SLC2A4,GLUT4,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Carbohydrate metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Endocrine and metabolic diseases,Diabetes,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiac metabolism,SLC2A4

Poids moléculaire: 43 kDa/54 kDa

ID gène: 6517

UniProt: P14672

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg