HSP90AB1 anticorps (N-Term)

N° du produit ABIN614808

Détail du produit anti-HSP90AB1 anticorps

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP90AB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: EEVHHGEEEV EC

Specificité: This antibody recognizes the EEVHHG epitope within the N-terminal part of Hsp90 beta an ubiquitously expressed protein with calculated Mw of 83.3 kDa, however, migrating as a 90 kDa band under reducing SDS-PAGE conditions.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Bovine

Purification: Protein-A affinity chromatography

Pureté: > 95 % pure by SDS-PAGE

Immunogène: Peptide within N-terminal part of human Hsp90

Clone: MBH90B

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur HSP90AB1

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Autre désignation: HSP90AB1 / HSP90 beta (HSP90AB1 Produits)

Synonymes: anticorps D6S182, anticorps HSP84, anticorps HSP90B, anticorps HSPC2, anticorps HSPCB, anticorps GRP94, anticorps TRA1, anticorps hsp90b, anticorps 90kDa, anticorps AL022974, anticorps C81438, anticorps Hsp84, anticorps Hsp84-1, anticorps Hsp90, anticorps Hspcb, anticorps Hsp70, anticorps Hsp70-1, anticorps Hsp70.1, anticorps hsp68, anticorps HSP90-BETA, anticorps hsp90beta, anticorps wu:fa29f01, anticorps wu:fa91e11, anticorps wu:fd59e11, anticorps wu:gcd22h07, anticorps HSP90, anticorps heat shock protein 90 alpha family class B member 1, anticorps heat shock protein 90 beta family member 1, anticorps Heat Shock Protein 90, endoplasmic reticulum, anticorps heat shock protein 90B, anticorps heat shock protein 90 alpha (cytosolic), class B member 1, anticorps heat shock protein 1B, anticorps heat shock protein 90kDa alpha family class B member 1 S homeolog, anticorps heat shock protein 90, alpha (cytosolic), class B member 1, anticorps HSP90AB1, anticorps HSP90B1, anticorps HSP90B, anticorps hsp90ab1, anticorps Hsp90ab1, anticorps Hspa1b, anticorps hsp90ab1.S

Sujet: Hsp90 beta (heat shock protein 90 beta) is a constitutively expressed isoform of Hsp90, one of the most abundant chaperones in the cytosol of eukaryotic cells. Hsp90 interacts with various proteins, including protein kinases and transcription factors, and either facilitates their stabilization and activation or directs them for proteasomal degradation. Hsp90 thus affects multiple signaling pathways and biological processes and modulation of this single target offers the prospect of simultaneous intervence to various key points of oncogenic transformation. Hsp90 operates as a dimer in a conformational cycle driven by ATP binding and hydrolysis.Synonyms: HSP84, HSP90B, HSPC2, HSPCB, Heat shock 84 kDa, Heat shock protein HSP 90-beta

ID gène: 3326

NCBI Accession: NP_031381

UniProt: P08238

Pathways: Regulation of Cell Size