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SMAD7 anticorps (AA 1-100)

SMAD7 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6148093
  • Antigène Voir toutes SMAD7 Anticorps
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Épitope
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 46
    • 26
    • 24
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 39
    • 7
    Lapin
    Clonalité
    • 40
    • 6
    Polyclonal
    Conjugué
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMAD7 est non-conjugé
    Application
    • 26
    • 17
    • 14
    • 14
    • 10
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MFRTKRSALV RRLWRSRAPG GEDEEEGAGG GGGGGELRGE GATDSRAHGA GGGGPGRAGC CLGKAVRGAK GHHHPHPPAA GAGAAGGAEA DLKALTHSVL
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad7 (NP_005895.1).
    Isotype
    IgG
    Top Product
    Discover our top product SMAD7 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Autre désignation
    SMAD7 (SMAD7 Produits)
    Synonymes
    anticorps CRCS3, anticorps MADH7, anticorps MADH8, anticorps Smad7a, anticorps Madh7, anticorps Smad10, anticorps madh7, anticorps xsmad7, anticorps wu:fj60c10, anticorps SMAD family member 7, anticorps SMAD family member 7 L homeolog, anticorps SMAD7, anticorps Smad7, anticorps smad7.L, anticorps smad7
    Sujet
    The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.,SMAD7,CRCS3,MADH7,MADH8,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,SMADs,SMAD7
    Poids moléculaire
    23 kDa/46 kDa
    ID gène
    4092
    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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